EC 1.14.13.39 - L- arginine,NADPH:oxygen oxidoreductase (nitric- oxide- forming) (nitric- oxide synthase)

3D structures of EC 1.14.13.39 - nitric-oxide synthase in Protein Data Bank

updated: 17 May 2012, 1:59

1. 1d0c: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 3- Bromo-7-nitroindazole (H4B Free)
2. 1d0o: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 3- Bromo-7-nitroindazole (H4B Present)
3. 1d1v: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with S- Ethyl-n-phenyl-isothiourea (H4B Bound)
4. 1d1w: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 2- Aminothiazoline (H4B Bound)
5. 1d1x: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 1, 4-pbitu (H4B Bound)
6. 1d1y: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 1, 3-pbitu (H4B Free)
7. 1dd7: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) (n-[(1,3-benzodioxol-5-yl)methyl]-1-[2-(1h- Imidazol-1-yl)pyrimidin-4-yl]-4-(methoxycarbonyl)- Piperazine-2-acetamide Complex
8. 1df1: Murine Inosoxy Dimer with Isothiourea Bound in The Active Site
9. 1dm6: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with N-(4-chlorophenyl)-n'-hydroxyguanidine (H4B Free)
10. 1dm7: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with Homoarginine (H4B Free)
11. 1dm8: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 1,2,4-triazole-carboxamidine (H4B Bound)
12. 1dmi: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6S-H4B
13. 1dmj: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 5,6-cyclic-tetrahydropteridine
14. 1dmk: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 4-amino-6-phenyl-tetrahydropteridine
15. 1dwv: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer N-hydroxyarginine and 4-amino Tetrahydrobiopterin
16. 1dww: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer N-hydroxyarginine and Dihydrobiopterin
17. 1dwx: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer N-hydroxyarginine and Tetrahydrobiopterin
18. 1ed4: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with Ipitu (H4B Free)
19. 1ed5: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with NNA(H4B Free)
20. 1ed6: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with L-nio (H4B Free)
21. 1f20: Crystal Structure of Rat Neuronal Nitric-oxide Synthase Fad/nadp+ Domain at 1.9a Resolution.
22. 1foi: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 1400W(H4B-FREE)
23. 1foj: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with 7-nitroindazole-2-carboxamidine (H4B Present)
24. 1fol: Reduced Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with L-ARG(H4B-FREE)
25. 1foo: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with L-arg and NO(H4B-FREE)
26. 1fop: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with L-arg and NO(H4B-BOUND)
27. 1i83: Bovine Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1,n14-bis((s-methyl)isothioureido) Tetradecane (H4B Free)
28. 1jwj: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with W457F Mutation at Tetrahydrobiopterin Binding Site
29. 1jwk: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with W457A Mutation at Tetrahydrobiopterin Binding Site
30. 1k2r: Structure of Rat Brain Nnos Heme Domain Complexed with Ng- Nitro-l-arginine
31. 1k2s: Structure of Rat Brain Nnos Heme Domain Complexed with Ng- Allyl-l-arginine
32. 1k2t: Structure of Rat Brain Nnos Heme Domain Complexed with S- Ethyl-n-phenyl-isothiourea
33. 1k2u: Structure of Rat Brain Nnos Heme Domain Complexed with S- Ethyl-n-[4-(trifluoromethyl)phenyl] Isothiourea
34. 9nse: Bovine Endothelial Nitric Oxide Synthase, Ethyl- Isoselenourea Complex
35. 8nse: Bovine Endothelial Nitric Oxide Synthase, Nna Complex
36. 7nse: Bovine Endothelial Nitric Oxide Synthase, H4B-FREE, Adma Complex
37. 6nse: Bovine Endothelial Nitric Oxide Synthase, H4B-FREE, Canavanine Complex
38. 5nse: Bovine Endothelial Nitric Oxide Synthase, H4B-FREE, Hydroxy- Arg Complex
39. 4nse: Bovine Endothelial Nitric Oxide Synthase, H4B-FREE, L-arg Complex
40. 4nos: Human Inducible Nitric Oxide Synthase with Inhibitor
41. 3nse: Bovine Enos, H4B-FREE, Seitu Complex
42. 3nqs: Crystal Structure of Inducible Nitric Oxide Synthase with N- Nitrosated-pterin
43. 3nos: Human Endothelial Nitric Oxide Synthase with Arginine Substrate
44. 3nod: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with Tetrahydrobiopterin and Product Analogue L- Thiocitrulline
45. 3nnz: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain Complexed with 6-(((3s,4s)-4-(2-(3-fluorophenethylamino)ethoxy)pyrrolidin-3- Yl)methyl)pyridin-2-amine
46. 3nny: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain Complexed with 6-(((3r,4r)-4-(2-(3-fluorophenethylamino)ethoxy)pyrrolidin-3- Yl)methyl)pyridin-2-amine
47. 3nlr: Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with 6-{{(3'r,4's)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine
48. 3nlq: Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with 6-{{(3'r,4'r)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine
49. 3nlp: Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with 6-{{(3's,4's)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine
50. 1lzx: Rat Neuronal Nos Heme Domain with Ng-hydroxy-l-arginine Bound
51. 3nlo: Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3's,4'r)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
52. 1lzz: Rat Neuronal Nos Heme Domain with N-isopropyl-n'-hydroxyguanidine Bound
53. 3nln: Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3'r,4's)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
54. 1m00: Rat Neuronal Nos Heme Domain with N-butyl-n'-hydroxyguanidine Bound
55. 3nlm: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-{{(3'r,4'r)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
56. 3nlk: Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with 6-{{(3's,4's)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
57. 3nlj: Structure of Neuronal Nitric Oxide Synthase D597N/M336V/Y706A Triple Mutant Heme Domain Complexed with 6-{{(3'r,4'r)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy] Pyrrolidin-4'-yl}methyl}-4- Methylpyridin-2-amine
58. 3nli: Structure of Endothelial Nitric Oxide Synthase N368D Mutant Heme Domain Complexed with 6-{{(3'r,4'r)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine
59. 3nlh: Structure of Endothelial Nitric Oxide Synthase Heme Domain N368D Mutant Complexed with 6-{{(3's,4's)-3'-[2"-(3'''- Fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin- 2-amine
60. 3nlg: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3's,4'r)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
61. 3nlf: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'r,4's)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
62. 3nle: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3'r,4'r)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
63. 3nld: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6-{{(3's,4's)-3'-[2"-(3'''-fluorophenethylamino) Ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
64. 1m7v: Structure of a Nitric Oxide Synthase Heme Protein from Bacillus Subtilis with Tetrahydrofolate and Arginine Bound
65. 1m7z: Structure of Nitric Oxide Synthase Heme Protein from Bacillus Subtilis with N-hydroxy-arginine and Tetrahydrofolate Bound
66. 1m8d: Inducible Nitric Oxide Synthase with Chlorzoxazone Bound
67. 1m8e: Inducible Nitric Oxide Synthase with 7-nitroindazole Bound
68. 1m8h: Inducible Nitric Oxide Synthase with 6-nitroindazole Bound
69. 1m8i: Inducible Nitric Oxide Synthase with 5-nitroindazole Bound
70. 1m9j: Human Endothelial Nitric Oxide Synthase with Chlorzoxazone Bound
71. 1m9k: Human Endothelial Nitric Oxide Synthase with 7- Nitroindazole Bound
72. 1m9m: Human Endothelial Nitric Oxide Synthase with 6- Nitroindazole Bound
73. 1m9q: Human Endothelial Nitric Oxide Synthase with 5- Nitroindazole Bound
74. 1m9r: Human Endothelial Nitric Oxide Synthase with 3-bromo-7- Nitroindazole Bound
75. 1m9t: Inducible Nitric Oxide Synthase with 3-bromo-7- Nitroindazole Bound
76. 3n2r: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r/3s,4s)-4-(3-phenoxyphenoxy)pyrrolidin-3-yl)methyl) Pyridin-2-amine
77. 1mjt: Crystal Structure of Sanos, a Bacterial Nitric Oxide Synthase Oxygenase Protein, in Complex with Nad+ and Seitu
78. 1mmv: Rat Neuronal Nos Heme Domain with Ng-propyl-l-arginine Bound
79. 1mmw: Rat Neuronal Nos Heme Domain with Vinyl-l-nio Bound
80. 1n2n: Crystal Structure of Cyanide Complex of The Oxygenase Domain of Inducible Nitric Oxide Synthase.
81. 1niw: Crystal Structure of Endothelial Nitric Oxide Synthase Peptide Bound to Calmodulin
82. 1noc: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) Complexed with Type I E. Coli Chloramphenicol Acetyl Transferase and Imidazole
83. 1nod: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with Tetrahydrobiopterin and Substrate L- Arginine
84. 1nos: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114), Imidazole Complex
85. 1nse: Bovine Endothelial Nitric Oxide Synthase
86. 1nsi: Human Inducible Nitric Oxide Synthase, Zn-bound, L-arg Complex
87. 1om4: Structure of Rat Neuronal Nos Heme Domain with L-arginine Bound
88. 1om5: Structure of Rat Neuronal Nos Heme Domain with 3-bromo-7- Nitroindazole Bound
89. 3jx6: Structure of Neuronal Nitric Oxide Synthase D597N/M336V/Y706A Mutant Heme Domain Complexed with N1-[(3' R,4' R)-4'-((6"-amino-4"- Methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl) Ethane-1,2-diamine Tetrahydrochloride
90. 3jx5: Structure of Rat Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with N1-{(3's,4'r)-4'-[(6"-amino-4"- Methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl) Ethane-1,2-diamine
91. 3jx4: Structure of Rat Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with N1-{(3'r,4's)-4'-[(6"-amino-4"- Methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl) Ethane-1,2-diamine
92. 3jx3: Structure of Rat Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with N1-{(3'r,4'r)-4'-[(6"-amino-4"- Methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl) Ethane-1,2-diamine
93. 3jx2: Structure of Rat Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with N1-{(3's,4's)-4'-[(6"-amino-4"- Methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl) Ethane-1,2-diamine
94. 3jx1: Structure of Rat Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex with N1-{(3'r,4'r)-4'-[(6"-amino-4"-methylpyridin- 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- Diamine
95. 3jx0: Structure of Rat Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex with N1-{(3's,4's)-4'-[(6"-amino-4"-methylpyridin- 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- Diamine
96. 3jwz: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-[(3' S,4' R)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl) Pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
97. 3jwy: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-{(3'r,4's)-4'-[(6"-amino-4"-methylpyridin-2"-yl) Methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
98. 3jwx: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-[(3'r,4'r)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl) Pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
99. 3jww: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-[(3's,4's)-4'-((6"-amino-4"-methylpyridin-2"-yl)methyl) Pyrrolidin-3'-yl]-n2- (3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
100. 3jwv: Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with N1-{(3's,4'r)-4'-[(6"-amino-4"-methylpyridin- 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- Diamine
101. 3jwu: Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with N1-{(3'r,4's)-4'-[(6"-amino-4"-methylpyridin- 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- Diamine Tetrahydrochloride
102. 3jwt: Structure of Rat Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain in Complex with N1-{(3'r,4'r)-4'-[(6"-amino-4"-methylpyridin- 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- Diamine
103. 3jws: Structure of Neuronal Nitric Oxide Synthase R349A Mutant Heme Domain Complexed with N1-[(3' S,4's)-4'-((6"-amino-4"-methylpyridin-2"-yl) Methyl)pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
104. 3jta: Structure of Neuronal Nitric Oxide Synthase Heme Domain in The Ferrous State Complexed with N~5~-[4-(methylsulfanyl) Butanimidoyl]-l-ornithine
105. 3jt9: Structure of Neuronal Nitric Oxide Synthase Heme Domain in The Ferrous State Complexed with N~5~-[2-(ethylsulfanyl) Ethanimidoyl]-l-ornithine
106. 3jt8: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-{3-[(1-methylethyl) Sulfanyl]propanimidoyl}-l-ornithine
107. 3jt7: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(propylsulfanyl)ethanimidoyl]-l- Ornithine
108. 3jt6: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[4-(methylsulfanyl)butanimidoyl]-l- Ornithine
109. 3jt5: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(ethylsulfanyl)ethanimidoyl]-l- Ornithine
110. 3jt4: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[(3-(ethylsulfanyl)propanimidoyl]-l- Ornithine
111. 3jt3: Structure of Neuronal Nitric Oxide Synthase Heme Domain Complexed with N~5~-[2-(methylsulfanyl)ethanimidoyl]-l- Ornithine
112. 1p6h: Rat Neuronal Nos Heme Domain with L-n(omega)-nitroarginine- 2,4-l-diaminobutyric Amide Bound
113. 1p6i: Rat Neuronal Nos Heme Domain with (4s)-n-(4-amino-5- [aminoethyl]aminopentyl)-n'-nitroguanidine Bound
114. 1p6j: Rat Neuronal Nos Heme Domain with L-n(omega)-nitroarginine- (4r)-amino-l-proline Amide Bound
115. 1p6k: Rat Neuronal Nos D597N Mutant Heme Domain with L-n(omega)- Nitroarginine-2,4-l-diaminobutyric Amide Bound
116. 1p6l: Bovine Endothelial Nos Heme Domain with L-n(omega)- Nitroarginine-2,4-l-diaminobutyric Amide Bound
117. 1p6m: Bovine Endothelial Nos Heme Domain with (4s)-n-(4-amino-5- [aminoethyl]aminopentyl)-n'-nitroguanidine Bound
118. 1p6n: Bovine Endothelial Nos Heme Domain with L-n(omega)- Nitroarginine-(4r)-amino-l-proline Amide Bound
119. 1q2o: Bovine Endothelial Nitric Oxide Synthase N368D Mutant Heme Domain Dimer with L-n(omega)-nitroarginine-2,4-l- Diaminobutyramide Bound
120. 3hsp: Ternary Structure of Neuronal Nitric Oxide Synthase with Nha and No Bound(2)
121. 3hso: Ternary Structure of Neuronal Nitric Oxide Synthase with Nha and No Bound(1)
122. 3hsn: Ternary Structure of Neuronal Nitric Oxide Synthase with Nha and Co Bound
123. 3hr4: Human Inos Reductase and Calmodulin Complex
124. 1qom: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with Swapped N-terminal Hook
125. 1qw4: Crystal Structure of Murine Inducible Nitric Oxide Synthase Oxygenase Domain in Complex with N-omega-propyl-l-arginine.
126. 1qw5: Murine Inducible Nitric Oxide Synthase Oxygenase Domain in Complex with W1400 Inhibitor.
127. 1qw6: Rat Neuronal Nitric Oxide Synthase Oxygenase Domain in Complex with N-omega-propyl-l-arg.
128. 1qwc: Rat Neuronal Nitric Oxide Synthase Oxygenase Domain in Complex with W1400 Inhibitor.
129. 1r35: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer, Tetrahydrobiopterin and 4r-fluoro-n6-ethanimidoyl-l-lysine
130. 3gof: Calmodulin Bound to Peptide from Macrophage Nitric Oxide Synthase
131. 1rs6: Rat Neuronal Nos Heme Domain with D-lysine-d-nitroarginine Amide Bound
132. 1rs7: Rat Neuronal Nos Heme Domain with D-phenylalanine-d- Nitroarginine Amide Bound
133. 1rs8: Bovine Endothelial Nos Heme Domain with D-lysine-d- Nitroarginine Amide Bound
134. 1rs9: Bovine Endothelial Nos Heme Domain with D-phenylalanine-d- Nitroarginine Amide Bound
135. 3fc5: G586S Mutant Nnosoxy
136. 3ej8: Structure of Double Mutant of Human Inos Oxygenase Domain with Bound Immidazole
137. 3ebf: Structure of Inhibited Murine Inos Oxygenase Domain
138. 3ebd: Structure of Inhibited Murine Inos Oxygenase Domain
139. 1tll: Crystal Structure of Rat Neuronal Nitric-oxide Synthase Reductase Module at 2.3 a Resolution.
140. 3eai: Structure of Inhibited Murine Inos Oxygenase Domain
141. 3eah: Structure of Inhibited Human Enos Oxygenase Domain
142. 3e7t: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C102222
143. 3e7s: Structure of Bovine Enos Oxygenase Domain with Inhibitor Ar- C95791
144. 3e7m: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C95791
145. 3e7i: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C94864
146. 3e7g: Structure of Human Inosox with Inhibitor Ar-c95791
147. 3e6t: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C118901
148. 3e6o: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C124355
149. 3e6n: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C125813
150. 3e6l: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C132283
151. 3e68: Structure of Murine Inos Oxygenase Domain with Inhibitor Ar- C130232
152. 3e67: Murine Inos Dimer with Inhibitor 4-map Bound
153. 3e65: Murine Inos Dimer with Heme, Pterin and Inhibitor Ar-c120011
154. 3dwj: Heme-proximal W188H Mutant of Inducible Nitric Oxide Synthase
155. 3dqt: Structure of Endothelial Nos Heme Domain in Complex with a Inhibitor (+-)-n1-{trans-4'-[(6"-amino-4"-methylpyridin-2"- Yl)methyl]pyrrolidin-3'-yl}-n2-(3'-chlorobenzyl)ethane-1,2- Diamine
156. 3dqs: Structure of Endothelial Nos Heme Domain in Complex with a Inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"- Yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2- Diamine
157. 3dqr: Structure of Neuronal Nos D597N/M336V Mutant Heme Domain in Complex with a Inhibitor (+-)-n1-{cis-4'-[(6"-aminopyridin- 2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
158. 1vaf: Inducible Nitric Oxide Synthase Oxygenase Domain Complexed with The Inhibitor Ar-r17477
159. 1vag: Neuronal Nitric Oxide Synthase Oxygenase Domain Complexed with The Inhibitor Ar-r17477
160. 3b3p: Structure of Neuronal Nos Heme Domain in Complex with a Inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"- Yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2- Diamine
161. 3b3o: Structure of Neuronal Nos Heme Domain in Complex with a Inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"- Yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2- Diamine
162. 3b3n: Structure of Neuronal Nos Heme Domain in Complex with a Inhibitor (+-)-n1-{cis-4'-[(6"-aminopyridin-2"-yl) Methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
163. 3b3m: Structure of Neuronal Nos Heme Domain in Complex with a Inhibitor (+-)-3-{cis-4'-[(6"-aminopyridin-2"-yl) Methyl]pyrrolidin-3'-ylamino}propan-1-ol
164. 1zvi: Rat Neuronal Nitric Oxide Synthase Oxygenase Domain
165. 1zvl: Rat Neuronal Nitric Oxide Synthase Oxygenase Domain Complexed with Natural Substrate L-arg.
166. 1zzq: Rat Nnos D597N Mutant with L-n(omega)-nitroarginine-(4r)- Amino-l-proline Amide Bound
167. 1zzr: Rat Nnos D597N/M336V Double Mutant with L-n(omega)- Nitroarginine-(4r)-amino-l-proline Amide Bound
168. 1zzs: Bovine Enos N368D Single Mutant with L-n(omega)- Nitroarginine-(4r)-amino-l-proline Amide Bound
169. 1zzt: Bovine Enos N368D/V106M Double Mutant with L-n(omega)- Nitroarginine-(4r)-amino-l-proline Amide Bound
170. 1zzu: Rat Nnos D597N/M336V Double Mutant with L-n(omega)- Nitroarginine-2,4-l-diaminobutyric Amide Bound
171. 2amo: Loose Dimer of a Bacillus Subtilis Nitric Oxide Synthase
172. 2an0: Crystal Structure of The P332G Mutant of The Bacillus Subtilis Nos
173. 2an2: P332G, A333S Double Mutant of The Bacillus Subtilis Nitric Oxide Synthase
174. 2bhj: Murine Ino Synthase with Coumarin Inhibitor
175. 2ort: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) 1-benzo[1,3]dioxol-5-ylmethyl-3s-(4-imidazol-1- Yl-phenoxy)-piperidine Complex
176. 2ors: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) 4-(benzo[1,3]dioxol-5-yloxy)-2-(4-imidazol-1- Yl-phenoxy)-6-methyl-pyrimidine Complex
177. 2orr: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) 4-(benzo[1,3]dioxol-5-yloxy)-2-(4-imidazol-1- Yl-phenoxy)-pyrimidine Complex
178. 2orq: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) 4-(imidazol-1-yl)phenol and Piperonylamine Complex
179. 2orp: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) 2-[4-(2-imidazol-1-yl-6-methyl-pyrimidin-4-yl)- 1-isobutyryl-piperazin-2-yl]-n-[2-(4-methoxy-phenyl)- Ethyl]-acetamide Complex
180. 2oro: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114) (r)-1-(2-imidazol-1-yl-6-methyl-pyrimidin-4- Yl)-pyrrolidine-2-carboxylic Acid (2-benzo[1,3]dioxol-5-yl- Ethyl)-amide Complex
181. 2nsi: Human Inducible Nitric Oxide Synthase, Zn-free, Seitu Complex
182. 2nse: Bovine Endothelial Nitric Oxide Synthase Substrate Complex
183. 2nos: Murine Inducible Nitric Oxide Synthase Oxygenase Domain (delta 114), Aminoguanidine Complex
184. 2nod: Murine Inducible Nitric Oxide Synthase Oxygenase Dimer (delta 65) with Tetrahydrobiopterin and Water Bound in Active Center
185. 2fc1: Heme No Complex in Nos
186. 2fc2: No-heme Complex in a Bacterial Nitric Oxide Synthase. an Fe(iii)-no May Cause Nitrosation.
187. 2flq: Crystal Structure of Nitric Oxide Synthase from Geobacillus Stearothermophilus (atcc 12980) Complexed with L-arginine
188. 2g6h: Structure of Rat Nnos Heme Domain (bh4 Bound) in The Reduced Form
189. 2g6i: Structure of Rat Nnos Heme Domain (bh2-bound) in The Reduced Form
190. 2g6j: Structure of Rat Nnos (L337N) Heme Domain (4-aminobiopterin Bound) Complexed with No
191. 2g6k: Structure of Rat Nnos Heme Domain (bh4 Bound) Complexed with No
192. 2g6l: Structure of Rat Nnos Heme Domain (bh2 Bound) Complexed with No
193. 2g6m: Structure of Rat Nnos Heme Domain (bh4 Bound) Complexed with Co
194. 2g6n: Strcture of Rat Nnos Heme Domain (bh2 Bound) Complexed with Co
195. 2g6o: Structure of Bovine Enos Heme Domain (bh4-free) Complexed with Co
196. 2hx2: Bovine Enos Heme Domain Complexed with (4s)-n-{4-amino-5- [(2-aminoethyl)-hydroxyamino]-pentyl}-n'-nitroguanidine
197. 2hx3: Rat Nnos Heme Domain Complexed with (4s)-n-{4-amino-5-[(2- Aminoethyl)-hydroxyamino]-pentyl}-n'-nitroguanidine
198. 2hx4: Rat Nnos Heme Domain Complexed with 4-n-(nw-nitro-l- Argininyl)-trans-4-hydroxyamino-l-proline Amide
199. 3n5p: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl) Ethyl)-6-methylpyridin-2-amine
200. 3n5q: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4- Methylpyridin-2-amine)
201. 3n5r: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl)-6- Methylpyridin-2-amine
202. 3n5s: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl) Ethyl)-6-methylpyridin-2-amine
203. 3n5t: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4- Methylpyridin-2-amine)
204. 3n5v: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl)-6- Methylpyridin-2-amine
205. 3n5w: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis(4- Methylpyridin-2-amine)
206. 3n5x: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-3-yl) Ethyl)-6-methylpyridin-2-amine
207. 3n5y: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6,6'-(2,2'-(pyridine-2,6-diyl)bis(ethane-2,1-diyl))bis(4- Methylpyridin-2-amine)
208. 3n5z: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin-2-yl) Ethyl)-6-methylpyridin-2-amine
209. 3n60: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl))bis(4- Methylpyridin-2-amine)
210. 3n61: Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1- Diyl))bis(4-methylpyridin-2-amine)
211. 3n62: Structure of Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl)) Bis(4-methylpyridin-2-amine)
212. 3n63: Structure of Neuronal Nitric Oxide Synthase D597N/M336V Mutant Heme Domain in Complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane- 2,1-diyl))bis(4-methylpyridin-2-amine)
213. 3n64: Structure of Neuronal Nitric Oxide Synthase D597N Mutant Heme Domain in Complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1- Diyl))bis(4-methylpyridin-2-amine)
214. 3n65: Structure of Neuronal Nitric Oxide Synthase S602H Mutant Heme Domain in Complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl)) Bis(4-methylpyridin-2-amine)
215. 3n66: Structure of Neuronal Nitric Oxide Synthase S602H Mutant Heme Domain in Complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1- Diyl))bis(4-methylpyridin-2-amine)
216. 3n67: Structure of Endothelial Nitric Oxide Synthase N368D/V106M Double Mutant Heme Domain Complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene) Bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
217. 3n68: Structure of Endothelial Nitric Oxide Synthase Heme Domain N368D/V106M Double Mutant Complexed with 4-(3-(2-(6-amino-4-methylpyridin-2-yl) Ethyl)phenethyl)-6-methylpyridin-2-amine
218. 3n69: Structure of Endothelial Nitric Oxide Synthase N368D/V106M Double Mutant Heme Domain Complexed with 6,6'-(2,2'-(pyridine-3,5-diyl) Bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
219. 3n6a: Structure of Endothelial Nitric Oxide Synthase N368D/V106M Double Mutant Heme Domain Complexed with 4-(2-(5-(2-(6-amino-4- Methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine
220. 3n6b: Structure of Endothelial Nitric Oxide Synthase H373S Single Mutant Heme Domain Complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane- 2,1-diyl))bis(4-methylpyridin-2-amine)
221. 3n6c: Structure of Endothelial Nitric Oxide Synthase H373S Single Mutant Heme Domain Complexed with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl) Ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine
222. 3n6d: Structure of Endothelial Nitric Oxide Synthase H373S Single Mutant Heme Domain Complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene) Bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
223. 3n6e: Structure of Endothelial Nitric Oxide Synthase N368D Mutant Heme Domain Complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2, 1-diyl))bis(4-methylpyridin-2-amine)
224. 3n6f: Structure of Endothelial Nitric Oxide Synthase N368D Single Mutant Heme Domain Complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane- 2,1-diyl))bis(4-methylpyridin-2-amine)
225. 3n6g: Structure of Endothelial Nitric Oxide Synthase N368D Single Mutant Heme Domain Complexed with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl) Ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine
226. 3nlt: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-{(3's,4's)-4'-[(6"-amino-4"-methylpyridin-2"-yl) Methyl]pyrrolidin-3'-yl}- N2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
227. 3nlu: Structure of Endothelial Nitric Oxide Synthase Heme Domain Complexed with N1-{(3'r,4'r)-4'-[(6"-amino-4"-methylpyridin-2"-yl) Methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2-diamine Tetrahydrochloride
228. 3nlv: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3s,4s)-4-(2-(2,2-difluoro-2-(3-fluorophenyl)ethylamino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
229. 3nlw: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3s,4s)-4-(2-(2,2-difluoro-2-(piperidin-2-yl)ethylamino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
230. 3nlx: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2- (2,2-difluoro-2-(3-fluorophenyl)ethylamino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
231. 3nly: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2- (2,2-difluoro-2-(4-fluorophenyl)ethylamino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
232. 3nlz: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-(2,2-difluoro-2-phenylethylamino)ethoxy) Pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
233. 3nm0: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-(2,2-difluoro-2-phenylethylamino)ethoxy) Pyrrolidin-3-yl)methyl)-4-methyl-3,4,5,6-tetrahydropyridin-2-amine
234. 2y37: The Discovery of Novel, Potent and Highly Selective Inhibitors of Inducible Nitric Oxide Synthase (inos)
235. 3q99: Structure of Neuronal Nitric Oxide Synthase in The Ferric State in Complex with N~5~-[(3-(ethylsulfanyl)propanimidoyl]-l-ornithine
236. 3q9a: Structure of Neuronal Nitric Oxide Synthase in The Ferric State in Complex with N-5-[2-(ethylsulfanyl)ethanimidoyl]-l-ornithine
237. 3nw2: Novel Nanomolar Imidazopyridines as Selective Nitric Oxide Synthase (inos) Inhibitors: Sar and Structural Insights
238. 3svp: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(3-chloro-5-fluorophenyl) Ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
239. 3svq: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(2,3-difluorophenyl)ethyl) Amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
240. 3png: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2-fluoro-2-(3-fluorophenyl)ethyl)amino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
241. 3pnh: Structure of Bovine Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2-fluoro-2-(3-fluorophenyl) Ethyl) Amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
242. 3pne: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(3-chlorophenyl)ethyl)amino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
243. 3pnf: Structure of Rat Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(2-chlorophenyl)ethyl)amino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
244. 3tyl: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3s,4s)-4-(2-((2-fluorobenzyl)amino)ethoxy)pyrrolidin-3-yl) Methyl)-4-methylpyridin-2-amine
245. 3tym: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3s,4s)-4-(2-((2-methoxybenzyl)amino)ethoxy)pyrrolidin-3- Yl)methyl)-4-methylpyridin-2-amine
246. 3tyn: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 2-(((2-(((3s,4s)-4-((6-amino-4-methylpyridin-2-yl)methyl) Pyrrolidin-3-yl)oxy)ethyl)amino)methyl)phenol
247. 3tyo: Structure of Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3s,4s)-4-(2-((furan-2-ylmethyl)amino)ethoxy)pyrrolidin-3- Yl)methyl)-4-methylpyridin-2-amine
248. 3rqj: Structure of The Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((1s,2r)-2-(3-fluorophenyl)cyclopropylamino) Ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
249. 3rqk: Structure of The Neuronal Nitric Oxide Synthase Heme Domain in Complex with 4-methyl-6-(((3r,4r)-4-(2-((1s,2r/1r,2s)-2-m- Tolylcyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)pyridin-2-amine
250. 3rql: Structure of The Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((1s,2r/1r,2s)-2-(3-clorophenyl) Cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2- Amine
251. 3rqm: Structure of The Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-{[(3r,4r)-4-(2-{[(2r/2s)-1-(3-fluorophenyl)propan-2- Yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine
252. 3rqn: Structure of The Neuronal Nitric Oxide Synthase Heme Domain in Complex with 6-(((3*r*,4*r*)-4-(2-(((*s* )-1-(3-fluorophenyl)propan-2-yl) Amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
253. 3rqo: Structure of The Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-(((3r,4r)-4-(2-((1s,2r/1r,2s)-2-(3-clorophenyl) Cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2- Amine
254. 3rqp: Structure of The Endothelial Nitric Oxide Synthase Heme Domain in Complex with 6-{[(3r,4r)-4-(2-{[(2r/2s)-1-(3-fluorophenyl)propan-2- Yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-amine
255. 2ll6: Solution Nmr Structure of Cam Bound to Inos Cam Binding Domain Peptide
256. 2ll7: Solution Nmr Structure of Cam Bound to The Enos Cam Binding Domain Peptide