EC 3.1.1.7 - acetylcholine acetylhydrolase (acetylcholinesterase)

3D structures of EC 3.1.1.7 - acetylcholinesterase in Protein Data Bank

updated: 17 May 2012, 1:59

1. 1acj: Quaternary Ligand Binding to Aromatic Residues in The Active-site Gorge of Acetylcholinesterase
2. 1acl: Quaternary Ligand Binding to Aromatic Residues in The Active-site Gorge of Acetylcholinesterase
3. 1amn: Transition State Analog: Acetylcholinesterase Complexed with M-(n,n,n-trimethylammonio)trifluoroacetophenone
4. 1ax9: Acetylcholinesterase Complexed with Edrophonium, Laue Data
5. 1b41: Human Acetylcholinesterase Complexed with Fasciculin-ii, Glycosylated Protein
6. 1c2b: Electrophorus Electricus Acetylcholinesterase
7. 1c2o: Electrophorus Electricus Acetylcholinesterase
8. 1cfj: Methylphosphonylated Acetylcholinesterase (aged) Obtained by Reaction with O-isopropylmethylphosphonofluoridate (gb, Sarin)
9. 1dx4: Ache from Drosophila Melanogaster Complex with Tacrine Derivative 9-(3-phenylmethylamino)-1,2,3,4-tetrahydroacridine
10. 1dx6: Structure of Acetylcholinesterase Complexed with (-)-galanthamine at 2.3a Resolution
11. 1e3q: Torpedo Californica Acetylcholinesterase Complexed with BW284C51
12. 1e66: Structure of Acetylcholinesterase Complexed with (-)-huprine X at 2.1a Resolution
13. 1ea5: Native Acetylcholinesterase (e.c. 3.1.1.7) from Torpedo Californica at 1.8a Resolution
14. 1eea: Acetylcholinesterase
15. 1eve: Three Dimensional Structure of The Anti-alzheimer Drug, E2020 (aricept), Complexed with Its Target Acetylcholinesterase
16. 1f8u: Crystal Structure of Mutant E202Q of Human Acetylcholinesterase Complexed with Green Mamba Venom Peptide Fasciculin-ii
17. 1fss: Acetylcholinesterase (e.c. 3.1.1.7) Complexed with Fasciculin-ii
18. 1gpk: Structure of Acetylcholinesterase Complex with (+)-huperzine a at 2.1a Resolution
19. 1gpn: Structure of Acetylcholinesterase Complexed with Huperzine B at 2.35a Resolution
20. 1gqr: Acetylcholinesterase (e.c. 3.1.1.7) Complexed with Rivastigmine
21. 1gqs: Acetylcholinesterase (e.c. 3.1.1.7) Complexed with Nap
22. 1h22: Structure of Acetylcholinesterase (e.c. 3.1.1.7) Complexed with (s,s)-(-)-bis(10)-hupyridone at 2.15a Resolution
23. 1h23: Structure of Acetylcholinesterase (e.c. 3.1.1.7) Complexed with (s,s)-(-)-bis(12)-hupyridone at 2.15a Resolution
24. 1hbj: X-ray Crystal Structure of Complex between Torpedo Californica Ache and a Reversible Inhibitor, 4-amino-5-fluo Ro-2-methyl-3-(3-trifluoroacetylbenzylthiomethyl)quinoline
25. 1j06: Crystal Structure of Mouse Acetylcholinesterase in The Apo Form
26. 1j07: Crystal Structure of The Mouse Acetylcholinesterase- Decidium Complex
27. 1jjb: A Neutral Molecule in Cation-binding Site: Specific Binding of Peg-sh to Acetylcholinesterase from Torpedo Californica
28. 1maa: Mouse Acetylcholinesterase Catalytic Domain, Glycosylated Protein
29. 1mah: Fasciculin2-mouse Acetylcholinesterase Complex
30. 1n5m: Crystal Structure of The Mouse Acetylcholinesterase- Gallamine Complex
31. 1n5r: Crystal Structure of The Mouse Acetylcholinesterase- Propidium Complex
32. 3lii: Recombinant Human Acetylcholinesterase
33. 1oce: Acetylcholinesterase (e.c. 3.1.1.7) Complexed with Mf268
34. 1odc: Structure of Acetylcholinesterase (e.c. 3.1.1.7) Complexed with N-4'-quinolyl-n'-9"-(1",2",3",4" -tetrahydroacridinyl)-1,8-diaminooctane at 2.2a Resolution
35. 3i6z: 3d Structure of Torpedo Californica Acetylcholinesterase Complexed with N-saccharinohexyl-galanthamine
36. 3i6m: 3d Structure of Torpedo Californica Acetylcholinesterase Complexed with N-piperidinopropyl-galanthamine
37. 1q83: Crystal Structure of The Mouse ACETYLCHOLINESTERASE-TZ2PA6 Syn Complex
38. 1q84: Crystal Structure of The Mouse ACETYLCHOLINESTERASE-TZ2PA6 anti Complex
39. 1qid: Specific Chemical and Structural Damage at Nine Time Points (point A) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
40. 1qie: Specific Chemical and Structural Damage at Nine Time Points (point B) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
41. 1qif: Specific Chemical and Structural Damage at Nine Time Points (point C) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
42. 1qig: Specific Chemical and Structural Damage at Nine Time Points (point D) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
43. 1qih: Specific Chemical and Structural Damage at Nine Time Points (point E) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
44. 1qii: Specific Chemical and Structural Damage at Nine Time Points (point F) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
45. 1qij: Specific Chemical and Structural Damage at Nine Time Points (point G) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
46. 1qik: Specific Chemical and Structural Damage at Nine Time Points (point H) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
47. 1qim: Specific Chemical and Structural Damage at Nine Time Points (point I) Caused by Intense Synchrotron Radiation to Torpedo Californica Acetylcholinesterase
48. 1qo9: Native Acetylcholinesterase from Drosophila Melanogaster
49. 1qon: Ache from Drosophila Melanogaster Complex with Tacrine Derivative 9-(3-iodobenzylamino)-1,2,3,4-tetrahydroacridine
50. 1qti: Acetylcholinesterase (e.c.3.1.1.7)
51. 3gel: O-methylphosphorylated Torpedo Acetylcholinesterase Obtained by Reaction with Methyl Paraoxon (aged)
52. 1som: Torpedo Californica Acetylcholinesterase Inhibited by Nerve Agent Gd (soman).
53. 1u65: Ache W. Cpt-11
54. 3dl7: Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update
55. 3dl4: Non-aged Form of Mouse Acetylcholinesterase Inhibited by Tabun- Update
56. 1ut6: Structure of Acetylcholinesterase (e.c. 3.1.1.7) Complexed with N-9-(1',2',3',4'-tetrahydroacridinyl)-1,8- Diaminooctane at 2.4 Angstroms Resolution.
57. 1vot: Acetylcholinesterase (e.c. 3.1.1.7) Complexed with Huperzine a
58. 1vxo: Methylphosphonylated Acetylcholinesterase (aged) Obtained by Reaction with O-ethyl-s-[2-[bis(1-methylethyl) Amino]ethyl] Methylphosphonothioate (vx)
59. 1vxr: O-ethylmethylphosphonylated Acetylcholinesterase Obtained by Reaction with O-ethyl-s-[2-[bis(1-methylethyl) Amino]ethyl] Methylphosphonothioate (vx)
60. 1vzj: Structure of The Tetramerization Domain of Acetylcholinesterase: Four-fold Interaction of a Www Motif with a Left-handed Polyproline Helix
61. 1w4l: Complex of Tcache with Bis-acting Galanthamine Derivative
62. 1w6r: Complex of Tcache with Galanthamine Derivative
63. 1w75: Native Orthorhombic Form of Torpedo Californica Acetylcholinesterase (ache)
64. 1w76: Orthorhombic Form of Torpedo Californica Acetylcholinesterase (ache) Complexed with Bis-acting Galanthamine Derivative
65. 2x8b: Crystal Structure of Human Acetylcholinesterase Inhibited by aged Tabun and Complexed with Fasciculin-ii
66. 2wu4: Crystal Structure of Mouse Acetylcholinesterase in Complex with Fenamiphos and Ortho-7
67. 2wu3: Crystal Structure of Mouse Acetylcholinesterase in Complex with Fenamiphos and Hi-6
68. 2wls: Crystal Structure of Mus Musculus Acetylcholinesterase in Complex with Amts13
69. 2whr: Crystal Structure of Acetylcholinesterase in Complex with K027
70. 2whq: Crystal Structure of Acetylcholinesterase, Phosphonylated by Sarin (aged) in Complex with Hi-6
71. 2whp: Crystal Structure of Acetylcholinesterase, Phosphonylated by Sarin and in Complex with Hi-6
72. 2wg2: Non-aged Conjugate of Torpedo Californica Acetylcholinesterase with Soman (alternative Refinement)
73. 2wg1: Ternary Complex of The aged Conjugate of Torpedo Californica Aceylcholinesterase with Soman and 2-pam
74. 2wg0: Aged Conjugate of Torpedo Californica Acetylcholinesterase with Soman (obtained by in Crystallo Aging)
75. 2wfz: Non-aged Conjugate of Torpedo Californica Acetylcholinesterase with Soman
76. 2w9i: Ache in Complex with Methylene Blue
77. 2w6c: Ache in Complex with a Bis-(-)-nor-meptazinol Derivative
78. 1zgb: Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex with an (r)-tacrine(10)- Hupyridone Inhibitor.
79. 1zgc: Crystal Structure of Torpedo Californica Acetylcholinesterase in Complex with an (rs)-tacrine(10)- Hupyridone Inhibitor.
80. 2vt7: Native Torpedo Californica Acetylcholinesterase Collected with a Cumulated Dose of 800000 Gy
81. 2vt6: Native Torpedo Californica Acetylcholinesterase Collected with a Cumulated Dose of 9400000 Gy
82. 2vq6: Torpedo Californica Acetylcholinesterase Complexed with 2- Pam
83. 2vjd: Torpedo Californica Acetylcholinesterase in Complex with a Non Hydrolysable Substrate Analogue, 4-oxo-n,n,n- Trimethylpentanaminium - Orthorhombic Space Group - Dataset C at 150k
84. 2vjc: Torpedo Californica Acetylcholinesterase in Complex with a Non Hydrolysable Substrate Analogue, 4-oxo-n,n,n- Trimethylpentanaminium - Orthorhombic Space Group - Dataset a at 150k
85. 2vjb: Torpedo Californica Acetylcholinesterase in Complex with a Non Hydrolysable Substrate Analogue, 4-oxo-n,n,n- Trimethylpentanaminium - Orthorhombic Space Group - Dataset D at 100k
86. 2vja: Torpedo Californica Acetylcholinesterase in Complex with a Non Hydrolysable Substrate Analogue, 4-oxo-n,n,n- Trimethylpentanaminium - Orthorhombic Space Group - Dataset a at 100k
87. 2ace: Native Acetylcholinesterase (e.c. 3.1.1.7) from Torpedo Californica
88. 2ack: Acetylcholinesterase Complexed with Edrophonium, Monochromatic Data
89. 2va9: Structure of Native Tcache after a 9 Seconds Annealing to Room Temperature during The First 5 Seconds of Which Laser Irradiation at 266nm Took Place
90. 2v98: Structure of The Complex of Tcache with 1-(2-nitrophenyl)-2, 2,2-trifluoroethyl-arsenocholine after a 9 Seconds Annealing to Room Temperature, during The First 5 Seconds of Which Laser Irradiation at 266nm Took Place
91. 2v97: Structure of The Unphotolysed Complex of Tcache with 1-(2- Nitrophenyl)-2,2,2-trifluoroethyl-arsenocholine after a 9 Seconds Annealing to Room Temperature
92. 2v96: Structure of The Unphotolysed Complex of Tcache with 1-(2- Nitrophenyl)-2,2,2-trifluoroethyl-arsenocholine at 100k
93. 2bag: 3d Structure of Torpedo Californica Acetylcholinesterase Complexed with Ganstigmine
94. 2c0p: Aged Form of Mouse Acetylcholinesterase Inhibited by Tabun
95. 2c0q: Non-aged Form of Mouse Acetylcholinesterase Inhibited by Tabun
96. 2c4h: Torpedo Californica Acetylcholinesterase in Complex with 500mm Acetylthiocholine
97. 2c58: Torpedo Californica Acetylcholinesterase in Complex with 20mm Acetylthiocholine
98. 2c5f: Torpedo Californica Acetylcholinesterase in Complex with a Non Hydrolysable Substrate Analogue, 4-oxo-n,n,n- Trimethylpentanaminium
99. 2c5g: Torpedo Californica Acetylcholinesterase in Complex with 20mm Thiocholine
100. 2cek: Conformational Flexibility in The Peripheral Site of Torpedo Californica Acetylcholinesterase Revealed by The Complex Structure with a Bifunctional Inhibitor
101. 2ckm: Torpedo Californica Acetylcholinesterase Complexed with Alkylene-linked Bis-tacrine Dimer (7 Carbon Linker)
102. 2cmf: Torpedo Californica Acetylcholinesterase Complexed with Alkylene-linked Bis-tacrine Dimer (5 Carbon Linker)
103. 2dfp: X-ray Structure of aged Di-isopropyl-phosphoro-fluoridate (dfp) Bound to Acetylcholinesterase
104. 2gyu: Crystal Structure of Mus Musculus Acetylcholinesterase in Complex with Hi-6
105. 2gyv: Crystal Structure of Mus Musculus Acetylcholinesterase in Complex with Ortho-7
106. 2gyw: Crystal Structure of Mus Musculus Acetylcholinesterase in Complex with Obidoxime
107. 2h9y: Crystal Structure of Mouse Acetylcholinesterase Complexed with M-(n,n,n-trimethylammonio)trifluoroacetophenone
108. 2ha0: Crystal Structure of Mouse Acetylcholinesterase Complexed with 4-ketoamyltrimethylammonium
109. 2ha2: Crystal Structure of Mouse Acetylcholinesterase Complexed with Succinylcholine
110. 2ha3: Crystal Structure of Mouse Acetylcholinesterase Complexed with Choline
111. 2ha4: Crystal Structure of Mutant S203A of Mouse Acetylcholinesterase Complexed with Acetylcholine
112. 2ha5: Crystal Structure of Mutant S203A of Acetylcholinesterase Complexed with Acetylthiocholine
113. 2ha6: Crystal Structure of Mutant S203A of Mouse Acetylcholinesterase Complexed with Succinylcholine
114. 2ha7: Crystal Structure of Mutant S203A of Mouse Acetylcholinesterase Complexed with Butyrylthiocholine
115. 2j3d: Native Monoclinic Form of Torpedo Acetylcholinesterase
116. 2j3q: Torpedo Acetylcholinesterase Complexed with Fluorophore Thioflavin T
117. 2j4f: Torpedo Acetylcholinesterase - Hg Heavy-atom Derivative
118. 2jey: Mus Musculus Acetylcholinesterase in Complex with Hlo-7
119. 2jez: Mus Musculus Acetylcholinesterase in Complex with Tabun and Hlo-7
120. 2jf0: Mus Musculus Acetylcholinesterase in Complex with Tabun and Ortho-7
121. 2jge: Crystal Structure of Mouse Acetylcholinesterase Inhibited by Non-aged Methamidophos
122. 2jgf: Crystal Structure of Mouse Acetylcholinesterase Inhibited by Non-aged Fenamiphos
123. 2jgg: Crystal Structure of Mouse Acetylcholinesterase Inhibited by Non-aged Sarin
124. 2jgh: Crystal Structure of Mouse Acetylcholinesterase Inhibited by Non-aged Vx
125. 2jgi: Crystal Structure of Mouse Acetylcholinesterase Inhibited by Non-aged Diisopropyl Fluorophosphate (dfp)
126. 2jgj: Crystal Structure of Mouse Acetylcholinesterase Inhibited by aged Methamidophos
127. 2jgk: Crystal Structure of Mouse Acetylcholinesterase Inhibited by aged Fenamiphos
128. 2jgl: Crystal Structure of Mouse Acetylcholinesterase Inhibited by aged Vx and Sarin
129. 2jgm: Crystal Structure of Mouse Acetylcholinesterase Inhibited by aged Diisopropyl Fluorophosphate (dfp)
130. 2xud: Crystal Structure of The Y337A Mutant of Mouse Acetylcholinesterase
131. 2xuf: Crystal Structure of MACHE-Y337A-TZ2PA6 anti Complex (1 Mth)
132. 2xug: Crystal Structure of MACHE-Y337A-TZ2PA6 anti Complex (1 Wk)
133. 2xuh: Crystal Structure of MACHE-Y337A-TZ2PA6 anti Complex (10 Mth)
134. 2xui: Crystal Structure of MACHE-Y337A-TZ2PA6 Syn Complex (1 Wk)
135. 2xuj: Crystal Structure of MACHE-Y337A-TZ2PA6 Syn Complex (1 Mth)
136. 2xuk: Crystal Structure of MACHE-Y337A-TZ2PA6 Syn Complex (10 Mth)
137. 2xuo: Crystal Structure of MACHE-Y337A Mutant in Complex with Soaked TZ2PA6 anti Inhibitor
138. 2xup: Crystal Structure of The MACHE-Y337A Mutant in Complex with Soaked TZ2PA6 Syn Inhibitor
139. 2xuq: Crystal Structure of The MACHE-Y337A Mutant in Complex with Soaked TZ2PA6 Anti-syn Inhibitors
140. 2xi4: Torpedo Californica Acetylcholinesterase in Complex with Aflatoxin B1 (orthorhombic Space Group)
141. 3m3d: Crystal Structure of Acetylcholinesterase in Complex with Xenon
142. 2y2u: Nonaged Form of Mouse Acetylcholinesterase Inhibited by Vx-update
143. 2y2v: Nonaged Form of Mouse Acetylcholinesterase Inhibited by Sarin-update
144. 4a23: Mus Musculus Acetylcholinesterase in Complex with Racemic C5685
145. 4a16: Structure of Mouse Acetylcholinesterase Complex with Huprine Derivative