EC 3.4.22.36 - caspase- 1

3D structures of EC 3.4.22.36 - caspase-1 in Protein Data Bank

updated: 9 February 2012, 15:47

1. 1bmq: Crystal Structure of The Complex of Interleukin-1beta Converting Enzyme (ice) with a Peptide Based Inhibitor, (3s )-n-methanesulfonyl-3-({1-[n-(2-naphtoyl)-l-valyl]-l- Prolyl }amino)-4-oxobutanamide
2. 1ibc: Crystal Structure of Inhibited Interleukin-1beta Converting Enzyme
3. 1ice: Structure and Mechanism of Interleukin-1beta Converting Enzyme
4. 1m72: Crystal Structure of Caspase-1 from Spodoptera Frugiperda
5. 1rwk: Crystal Structure of Human Caspase-1 in Complex with 3-(2- Mercapto-acetylamino)-4-oxo-pentanoic Acid
6. 1rwm: Crystal Structure of Human Caspase-1 in Complex with 4-oxo- 3-[2-(5-{[4-(quinoxalin-2-ylamino)-benzoylamino]-methyl}- Thiophen-2-yl)-acetylamino]-pentanoic Acid
7. 1rwn: Crystal Structure of Human Caspase-1 in Complex with 3-{2- Ethyl-6-[4-(quinoxalin-2-ylamino)-benzoylamino]- Hexanoylamino}-4-oxo-butyric Acid
8. 1rwo: Crystal Structure of Human Caspase-1 in Complex with 4-oxo- 3-{6-[4-(quinoxalin-2-ylamino)-benzoylamino]-2-thiophen-2- Yl-hexanoylamino}-pentanoic Acid
9. 1rwp: Crystal Structure of Human Caspase-1 in Complex with 3-{6- [(8-hydroxy-quinoline-2-carbonyl)-amino]-2-thiophen-2-yl- Hexanoylamino}-4-oxo-butyric Acid
10. 1rwv: Crystal Structure of Human Caspase-1 in Complex with 5-[5- (1-carboxymethyl-2-oxo-propylcarbamoyl)-5-phenyl- Pentylsulfamoyl]-2-hydroxy-benzoic Acid
11. 1rww: Crystal Structure of Human Caspase-1 in Complex with 4-oxo- 3-[(6-{[4-(quinoxalin-2-ylamino)-benzoylamino]-methyl}- Pyridine-3-carbonyl)-amino]-butyric Acid
12. 1rwx: Crystal Structure of Human Caspase-1 in Complex with 4-oxo- 3-{6-[4-(quinoxalin-2-yloxy)-benzoylamino]-2-thiophen-2-yl- Hexanoylamino}-butyric Acid
13. 1sc1: Crystal Structure of an Active-site Ligand-free Form of The Human Caspase-1 C285A Mutant
14. 1sc3: Crystal Structure of The Human Caspase-1 C285A Mutant in Complex with Malonate
15. 1sc4: Crystal Structure of The Human Caspase-1 C285A Mutant after Removal of Malonate
16. 3e4c: Procaspase-1 Zymogen Domain Crystal Strucutre
17. 3d6m: Crystal Structure of Human Caspase-1 with a Naturally- Occurring Lys319->arg Substitution in Complex with 3-[2-(2- Benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
18. 3d6h: Crystal Structure of Human Caspase-1 with a Naturally- Occurring Asn263->ser Substitution in Complex with 3-[2-(2- Benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
19. 3d6f: Crystal Structure of Human Caspase-1 with a Naturally- Occurring Arg240->gln Substitution in Complex with 3-[2-(2- Benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
20. 2nn3: Structure of Pro-sf-caspase-1
21. 2fqq: Crystal Structure of Human Caspase-1 (cys285->ala, Cys362- >ala, Cys364->ala, Cys397->ala) in Complex with 1-methyl-3- Trifluoromethyl-1h-thieno[2,3-c]pyrazole-5-carboxylic Acid (2-mercapto-ethyl)-amide
22. 2h48: Crystal Structure of Human Caspase-1 (cys362->ala, Cys364- >ala, Cys397->ala) in Complex with 3-[2-(2- Benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
23. 2h4w: Crystal Structure of Human Caspase-1 (glu390->asp) in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl- Butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad- Fmk)
24. 2h4y: Crystal Structure of Human Caspase-1 (arg286->lys) in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl- Butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad- Fmk)
25. 2h51: Crystal Structure of Human Caspase-1 (glu390->asp and Arg286->lys) in Complex with 3-[2-(2- Benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
26. 2h54: Crystal Structure of Human Caspase-1 (thr388->ala) in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl- Butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad- Fmk)
27. 2hbq: Crystal Structure of Wildtype Human Caspase-1 in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl-butyrylamino)- Propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
28. 2hbr: Crystal Structure of Human Caspase-1 (arg286->ala) in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl- Butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad- Fmk)
29. 2hby: Crystal Structure of Human Caspase-1 (glu390->ala) in Complex with 3-[2-(2-benzyloxycarbonylamino-3-methyl- Butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad- Fmk)
30. 2hbz: Crystal Structure of Human Caspase-1 (arg286->ala, Glu390- >ala) in Complex with 3-[2-(2-benzyloxycarbonylamino-3- Methyl-butyrylamino)-propionylamino]-4-oxo-pentanoic Acid (z-vad-fmk)
31. 3ns7: Succinic Acid Amides as P2-p3 Replacements for Inhibitors of Interleukin-1beta Converting Enzyme (ice or Caspase 1)